This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking any drug or commencing or discontinuing any course of treatment. Low sexual desire (libido) is a common type of sexual dysfunction in women and can be challenging to treat. Sexual dysfunction can refer to difficulties in libido (sex drive), arousal, or orgasm. There are many causes of sexual dysfunction. Psychiatric conditions such as depression or anxiety or emotional distress from work or relationship stressors are common causes. Some medical conditions can also affect sexual function, such as heart disease, certain neurological conditions, arthritis, or hormone changes during menopause. Medications, especially antidepressants, can also cause sexual dysfunction. Addressing the underlying medical or psychological issues improves sexual function in most women.
However, some women who have no other medical or psychological concerns still have low sexual desire that affects both their personal and relationship well-being. This condition is referred to as female sexual interest/arousal disorder. This is a new diagnosis in the Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition), which combined the previously separate disorders of hypoactive sexual desire disorder (HSDD) and female sexual arousal disorder.
The prevalence of these disorders varies widely depending on the population surveyed, but studies have suggested it can range anywhere from 5% to 15% of women. Treatment of HSDD and female sexual arousal disorder can be challenging. In August 2015, the US Food and Drug Administration (FDA) approved a medication called flibanserin to treat HSDD in premenopausal women, making it the first FDA-approved medication for low sexual desire in women. It is anticipated to be available in the United States in October 2015.
Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. Ask a clinical question libido booster for woman and tap into Healio AI's knowledge base. Flibanserin works by interacting with certain receptors for serotonin, a neurotransmitter that has a role in regulating mood, sleep, digestion, and many other functions of the body.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Kamagra Effervescent Tablets | 100 mg | 84 + 7 Pills | 202.91€ 193.25€ | |
| Kamagra Gold | 50 mg | 20 Pills | 73.17€ 69.69€ | |
| Cialis Professional | 20mg | 30 Pills | 104.57€ 99.59€ | |
| Levitra Professional | 20mg | 30 Pills | 119.12€ 113.45€ | |
| Cialis Generic | 2.5mg | 90 + 6 Pills | 112.43€ 107.08€ | |
| Viagra Original | 100mg | 120 + 8 Pills | 470.39€ 447.99€ | |
| Cialis Black | 80mg | 360 + 20 Pills | 639.78€ 609.31€ | |
| Cialis Soft Tabs | 20mg | 60 + 4 Pills | 159.37€ 151.78€ | |
| Cialis Generic | 5mg | 120 + 6 Pills | 132.92€ 126.59€ | |
| Viagra Oral Jelly | 100mg | 220 + 18 Sachets | 562.28€ 535.50€ | |
| Viagra Generic | 50mg | 180 + 8 Pills | 158.82€ 151.26€ | |
| Viagra Oral Jelly | 100mg | 90 + 8 Sachets | 258.02€ 245.73€ | |
| Kamagra Soft Tabs | 100 mg | 12 Pills | 57.55€ 54.81€ | |
| Apcalis SX Oral Jelly | 20mg | 120 + 13 Sachets | 280.38€ 267.03€ | |
| Cialis Generic | 5mg | 10 Pills | 29.39€ 27.99€ | |
| Kamagra Gold | 100 mg | 32 Pills | 121.24€ 115.47€ |
The exact way in which flibanserin leads to improved sexual desire in women is not clear, but studies have shown that it has a beneficial effect in women diagnosed as having HSDD. Flibanserin can have serious side effects, including low blood pressure and fainting.
Sex Med. Review Flibanserin for the treatment of hypoactive sexual desire disorder in premenopausal women. 2015]Review Flibanserin for the treatment of hypoactive sexual desire disorder in premenopausal women.Dhanuka I, Simon JA. Female Hypoactive Sexual Desire Disorder: A Practical Guide to Causes, Clinical Diagnosis, and Treatment. 2020]Female Hypoactive Sexual Desire Disorder: A Practical Guide to Causes, Clinical Diagnosis, and Treatment.Kingsberg SA, Simon JA.
This medication is used to treat women who have not gone through menopause who have low sexual desire and are concerned about it. Flibanserin should not be used to treat low sexual desire caused by: a medical or mental/mood disorder, problems in the relationship, or the effects of other drugs. This medication should not be used by women who have gone through menopause, or by men. Flibanserin is not used to enhance sexual performance. 100 mg Brand(s): Addyi(R), Sprout film-coated Read the Medication Guide provided by your pharmacist before you start taking flibanserin and each time you get a refill. The risk of these side effects increases with alcohol use, so alcohol absolutely cannot be combined with flibanserin.
| Side Effect | Frequency | Severity |
|---|---|---|
| Dizziness | Common | Mild to Moderate |
| Nausea | Common | Mild |
| Fatigue | Moderate | Mild |
| Sleepiness | Moderate | Mild |
Other medications including some birth control pills and antifungal agents can also increase the risk of these side effects. Women with liver problems should not take flibanserin. Because of these potentially serious side effects associated with alcohol use, not all doctors or pharmacies will be able to prescribe or dispense flibanserin. Because flibanserin is a new medication, continued postmarketing data collected by the FDA will be important. In the meantime, the FDA encourages the development of new drugs to treat female sexual disorders given the continued need for effective treatments.
If you miss a dose, skip the missed dose. Take your next dose at bedtime the next day. Do not double the dose to catch up. Warning: Breastfeeding is not recommended while using this drug. Alcohol and marijuana may intensify this effect.
Use care when operating a vehicle, vessel (e.g., boat), or machinery. If you drink alcohol, discuss the safe use of alcohol while using this medication with your healthcare professional. Do not eat grapefruit or drink grapefruit juice at any time while taking this medication. See also Warning and How to Use sections. Drug interactions may change how your medications work or increase your risk for serious side effects. To find this and previous JAMA Patient Pages, go to the Patient Page link on JAMA’s website at Spanish translations are available in the supplemental content tab. Flibanserin may cause very low blood pressure resulting in dizziness, lightheadedness, and fainting. Tell your doctor if you have or have ever had low blood pressure or any condition that can cause low blood pressure or if you drink or have ever drunk large amounts of alcohol.
| Aspect | Explanation |
|---|---|
| Serotonin Receptor Modulation | Acts as a 5-HT1A receptor agonist and 5-HT2A antagonist |
| Effect on Neurotransmitters | Balances serotonin, dopamine, and norepinephrine activity |
| Impact on Sexual Desire | Enhances desire by modulating serotonergic inhibition of dopamine pathways |
Drinking alcohol around the same time as taking flibanserin can increase the risk of having very low blood pressure. Wait at least 2 hours after drinking 1 or 2 alcoholic drinks before taking flibanserin at bedtime. If you drink 3 or more alcoholic drinks in the evening, skip your flibanserin dose on that evening. After taking flibanserin at bedtime, do not drink any alcohol until the next day.
Healio's exclusive daily news coverage of clinical data Selected from data included with permission and copyrighted by FDB, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution in professional health care settings. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of your healthcare professional. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you. You should consult your healthcare professional before taking any drug, changing your diet or commencing or discontinuing any course of treatment. If you have any of the following symptoms, call your doctor immediately and lie down: lightheadedness, fainting, or dizziness. Tell your doctor if you have or have ever had liver disease.
If you have any questions, ask your doctor or pharmacist. Take this medication by mouth as directed by your doctor, usually once daily at bedtime. Take flibanserin only at bedtime to reduce your risk of low blood pressure, fainting, and drowsiness while you are awake. After taking flibanserin, do not drink any alcohol until the next day. Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely.
Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details. Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Tell your doctor if your condition does not get better after 8 weeks of treatment. Your doctor will probably tell you not to take flibanserin. Some medications should not be taken with flibanserin. Other medications may cause dosing changes or extra monitoring when taken with flibanserin. Make sure you have discussed any medications you are currently taking or plan to take before starting flibanserin with your doctor and pharmacist.
This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Other medications can affect the removal of flibanserin from your body, which may affect how flibanserin works. Examples include azole antifungals (such as fluconazole, ketoconazole), certain calcium channel blockers (such as diltiazem, verapamil), macrolide antibiotics (such as clarithromycin, erythromycin), nefazodone, rifamycins (such as rifabutin, rifampin), ritonavir, St.
John's wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others. Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine). Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely. Store at room temperature away from light and moisture. Before starting, stopping, or changing any medications while taking flibanserin, please get the advice of your doctor or pharmacist. You will be given the Medication Guide. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit obtain the medication guide.
Flibanserin is used to treat certain women with hypoactive sexual desire disorder (HSDD; low sexual desire that causes distress or is troubling). Flibanserin should not be used for the treatment of HSDD in men or to improve sexual performance.