Tadalafil is not a standard treatment for COPD but may be used off-label. Consult your healthcare provider for more information. This is an off-label use and should only be taken under close medical supervision. 40 mg once daily for pulmonary hypertension.
| Population | Typical Dose Range | Notes |
|---|---|---|
| General adult males | 20mg - 40mg | Adjust based on response and tolerance |
| Elderly | Usually lower dose | Due to potential liver and kidney function changes |
| Patients with hepatic impairment | Usually start at lower doses | Monitor response closely |
| Patients with renal impairment | Dose adjustment may be necessary | Depends on severity |
For other types of hypertension, consult your healthcare provider for specific dosing recommendations. This is an off-label use and should be discussed with your doctor.
Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Talk to your doctor if you are using marijuana (cannabis). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). This medication can affect fertility in males. Discuss the use of reliable forms of birth control (such as condoms, birth control pills) before starting treatment, during treatment, and for 1 month after the last dose.
It is unknown if this medication passes into breast milk. Because of the possible risk to the infant, breastfeeding is not recommended while using this medication. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist.
Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug are: When used with nitrates, this medication can cause a serious drop in your blood pressure, which can lead to dizziness, fainting, and rarely heart attack or stroke. Do not use any of the following drugs during treatment with this medication or within 48 hours of your last dose of macitentan/tadalafil: certain drugs used to treat chest pain/angina (nitrates such as nitroglycerin, isosorbide) recreational drugs called "poppers" containing amyl or butyl nitrite If you are also taking an tadacip 20 mg tadalafil alpha blocker medication (such as doxazosin, tamsulosin) to treat an enlarged prostate/BPH or high blood pressure, your blood pressure may get too low which can lead to dizziness or fainting. Your doctor may adjust your medications to minimize your risk of low blood pressure. Other medications can affect the removal of macitentan/tadalafil from your body, which may affect how this medication works. 10 mg taken as needed before sexual activity.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Cialis Generic | 10mg | 270 + 10 Pills | 308.71€ 294.01€ | |
| Cialis Generic | 40mg | 20 Pills | 59.47€ 56.64€ | |
| Tadalista Super Active | 20mg | 270 + 30 Pills | 661.49€ 629.99€ | |
| Cialis Generic | 2.5mg | 270 + 10 Pills | 199.64€ 190.13€ | |
| Tadalista Super Active | 20mg | 120 + 16 Pills | 382.15€ 363.95€ | |
| Cialis Generic | 2.5mg | 120 + 6 Pills | 128.93€ 122.79€ | |
| Cialis Generic | 10mg | 360 + 10 Pills | 388.49€ 369.99€ | |
| Cialis Generic | 20mg | 90 + 6 Pills | 154.71€ 147.34€ | |
| Tadalista Super Active | 20mg | 180 + 20 Pills | 521.59€ 496.75€ | |
| Cialis Generic | 60mg | 360 + 10 Pills | 570.52€ 543.35€ | |
| Cialis Generic | 5mg | 60 + 4 Pills | 86.02€ 81.92€ | |
| Cialis Generic | 10mg | 20 Pills | 48.23€ 45.93€ | |
| Cialis Generic | 5mg | 30 + 4 Pills | 53.56€ 51.01€ | |
| Cialis Generic | 5mg | 90 + 6 Pills | 115.91€ 110.39€ | |
| Cialis Generic | 5mg | 180 + 10 Pills | 159.65€ 152.05€ |
The dose may be adjusted based on response and tolerability.
If this serious problem occurs, stop taking this medication and get medical help right away. You have a slightly greater chance of developing NAION if you have heart disease, diabetes, high cholesterol, certain other eye problems ("crowded disk"), high blood pressure, if you are over 50, or if you smoke. Rarely, a sudden decrease or loss of hearing, sometimes with ringing in the ears and dizziness, may occur. Stop taking this medication and get medical help right away if you get any of these side effects. Rarely, males may have a painful or prolonged erection lasting 4 or more hours.
If this occurs, stop using this drug and get medical help right away, or permanent problems could occur. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: itching/swelling (especially of the face/tongue/throat) This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. You may report side effects to FDA at 1-800-FDA-1088 or at In Canada - Call your doctor for medical advice about side effects.
You may report side effects to Health Canada at 1-866-234-2345. Before taking this medication, tell your doctor or pharmacist if you are allergic to macitentan or tadalafil; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: other lung conditions (such as pulmonary veno-occlusive disease) heart problems (such as angina, previous heart attack, irregular heartbeat, heart failure) penis conditions (such as angulation, fibrosis/scarring, Peyronie's disease) conditions that may increase the risk of priapism (such as sickle cell anemia, leukemia, multiple myeloma) eye problems (such as retinitis pigmentosa, sudden decreased vision, NAION) Alcohol or marijuana (cannabis) can make you more dizzy. This is an off-label use and should be taken under the guidance of a healthcare provider. Tadalafil tablets are available in the following strengths: 2.5 mg, 5 mg, 10 mg, and 20 mg. Tadalafil can be taken with or without food. If you are taking it for erectile dysfunction, take it at least 30 minutes before sexual activity. For daily use, take it at the same time each day. Do not split or crush the tablets. Always follow your healthcare provider’s instructions and consult them if you have any questions or concerns about your treatment.
Do not take this medication with any other product that contains tadalafil or other similar medications for erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, vardenafil). If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call 1-800-222-1222. Canada residents can call 1-844-764-7669.
Do not share this medication with others. Lab and/or medical tests (such as blood pressure, complete blood count, kidney/liver tests) may be done while you are taking this medication. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time.
Do not double the dose to catch up. Store in the original container at room temperature away from light and moisture. Keep the drying agent (desiccant) in the bottle. Tightly close the bottle when not in use. Keep all medications away from children and pets. Like all medications, Tadalafil can cause side effects. Most are mild, but some can be more serious.
| Recommendations | Details | Notes |
|---|---|---|
| Dose adherence | Take exactly as prescribed | Do not double doses |
| Timing with food | Can be taken with or without food | Food delays onset but does not reduce efficacy |
| Do not exceed recommended dose | Maximum is 40mg per dose | Risk of side effects |
| Avoid alcohol | May increase side effects | Reduce alcohol intake during treatment |
If you experience any side effects, contact your healthcare provider immediately.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you.
This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs. Selected from NATIONAL DRUG DATA FILE (NDDF) data included with permission and copyrighted by First Databank, Inc., 2019. This copyrighted material has been downloaded from a licensed data provider. The above information is intended to supplement, not substitute for, the expertise and judgment of your health care professional.
You should consult your health care professional before taking any drug, changing your diet, or commencing or discontinuing any course of treatment. It works by relaxing blood vessels, which improves blood flow to specific areas of the body. Tadalafil is available in various strengths and should always be taken as prescribed by your healthcare provider. It is important to consult your doctor before making any changes to your dosage. Our telemedicine providers are also available to help manage your treatment. Our telemedicine providers are available to assist you. Headache: A common side effect that usually resolves within a few hours. Flushing: Warmth or redness in the face, neck, or chest. Back pain: Muscle aches or discomfort, typically mild. Stuffy or runny nose: Nasal congestion or cold-like symptoms. Vision changes: Sudden vision loss or blurred vision.
As needed: 10 mg taken at least 30 minutes before sexual activity. The dose may be increased to 20 mg or reduced to 5 mg depending on how well it works and how well it is tolerated. Do not take more than one dose per day. Daily use: 2.5 mg once daily, taken at the same time each day, regardless of sexual activity. The dose may be increased to 5 mg based on individual response. Hearing loss: Sudden decrease or loss of hearing.
Prolonged erection (priapism): An erection lasting more than 4 hours.
5 mg once daily, taken at the same time each day. The duration of treatment depends on the severity of symptoms and how well the medication is working. 40 mg once daily (two 20 mg tablets). Do not split the dose or exceed 40 mg per day. 5 mg once daily, with potential adjustments based on individual response. This is a medical emergency and requires immediate treatment.
A contraindication is a specific condition where a medication should not be used due to potential harm. If you have any of the following conditions, you should not take Tadalafil, as it may pose serious health risks.
The generic name refers to the active ingredient, while the brand name is assigned by the manufacturer. The generic name is listed in parentheses. Tadalafil belongs to a class of medications known as Phosphodiesterase-5 (PDE5) inhibitors. Tadalafil is used to treat a variety of conditions, and the appropriate dosage depends on the condition being treated. Always consult your doctor or one tadalafil in women of our telemedicine providers before making any changes to your dose. Always consult your healthcare provider before starting any new medication, and if unsure, schedule a telemedicine appointment with one of our providers.